{"id":1884,"date":"2017-11-17T12:11:29","date_gmt":"2017-11-17T11:11:29","guid":{"rendered":"http:\/\/prager-elektronik.at.cloud3-vm432.de-nserver.de\/?post_type=product&#038;p=1884"},"modified":"2024-09-12T11:59:04","modified_gmt":"2024-09-12T09:59:04","slug":"mikrokalorimeter-peaq-itc-automated","status":"publish","type":"product","link":"https:\/\/www.prager-elektronik.at\/en\/produkte\/life-science\/mikrokalorimeter-von-malvern-panalytical-life-sciences\/mikrokalorimeter-peaq-itc-automated\/","title":{"rendered":"MicroCal PEAQ-ITC Automated"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1484828983369{margin-bottom: 25px !important;}&#8221;]<div class=\"title-wrapper  basel-title-color-default basel-title-style-default basel-title-size-small text-left \"><div class=\"liner-continer\"> <span class=\"left-line\"><\/span> <h4 class=\"title\" >MicroCal PEAQ-ITC Automated<span class=\"title-separator\"><span><\/span><\/span><\/h4> <span class=\"right-line\"><\/span> <\/div><\/div>[vc_column_text]The MicroCal PEAQ-ITC Automated is a configurable, low volume, highly sensitive isothermal titration calorimeter which offers the convenience of unattended operation. It delivers direct, label-free in solution measurement of all binding parameters in a single experiment. Applications include characterizing molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules. It can also be used to measure enzyme kinetics.<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1484828978370{margin-bottom: 25px !important;}&#8221;]<div class=\"title-wrapper  basel-title-color-default basel-title-style-default basel-title-size-small text-left \"><div class=\"liner-continer\"> <span class=\"left-line\"><\/span> <h4 class=\"title\" >Infos \/ Datasheet<span class=\"title-separator\"><span><\/span><\/span><\/h4> <span class=\"right-line\"><\/span> <\/div><\/div>[vc_column_text el_class=&#8221;responsive-table&#8221;]<\/p>\n<ul>\n<li class=\"pdf\"><a href=\"https:\/\/www.prager-elektronik.at\/wp-content\/uploads\/PEAQ-ITC-brochure-A4.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">MicroCal-ITC Datasheet<\/a><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]The MicroCal PEAQ-ITC Automated combines the high sensitivity of the MicroCal PEAQ-ITC \u2013 the calorimeter core of the system \u2013 with walkaway automation, to meet the productivity needs of busy research and drug discovery laboratories.<\/p>\n<p>The system directly measures heat released or absorbed during biochemical binding events, from which it calculates binding affinity (K<sub>D<\/sub>), stoichiometry (n), enthalpy (\u0394H), and entropy (\u0394S). Other than preparing samples and reagents to appropriate concentrations, there is minimal assay development and time to first result is fast. Easy-to use software includes optimized automation scripts for robust operation with a variety of sample types and conditions.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<strong>Features and benefits <\/strong><\/p>\n<ul>\n<li>User-friendly design tools assist in selecting experimental run parameters<\/li>\n<li>All binding parameters (affinity, stoichiometry, enthalpy and entropy) in a single experiment<\/li>\n<li>Quick to first result with minimal assay development, no labelling, no immobilization and no limitations due to molecular weight or optical properties<\/li>\n<li>High signal to noise gives more confidence in accessing data quality and relevance of generated affinity and thermodynamic parameters<\/li>\n<li>Outstanding data quality for sub-millimolar to picomolar disassociation constants (10<sup>\u20112 <\/sup>to 10<sup>\u201112<\/sup> M)<\/li>\n<li>Coin shaped cell optimizes sample mixing<\/li>\n<li>Nonreactive Hastelloy for chemical resistance and compatibility with biological samples<\/li>\n<li>Sensitivity to investigate any biomolecular interaction using as little as 10 \u00b5g of protein<\/li>\n<li>Samples presented in temperature controlled 96-well plate<\/li>\n<li>Fully automated system with walk-away operation for enhanced productivity<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<strong>PEAQ ITC Software<\/strong><\/p>\n<p>MicroCal PEAQ-ITC software offers experiment design simulation, batch evaluation of large data sets, automated assessment of data quality and a streamlined user interface that guides the user to final figures and presentation quality graphs quickly and easily.<\/p>\n<ul>\n<li>Open multiple experiments in a single session<\/li>\n<li>Supports many automated fitting models\n<ul>\n<li>Dissociation<\/li>\n<li>Enzyme Kinetics &#8211; Multiple Injections<\/li>\n<li>Enzyme Kinetics &#8211; Single Injection<\/li>\n<li>One Set of Sites<\/li>\n<li>Sequential Binding Sites<\/li>\n<li>One Set of Sites &#8211; SIM<\/li>\n<li>Two Sets of Sites<\/li>\n<li>Competitive<\/li>\n<\/ul>\n<\/li>\n<li>Automated assessment of data quality\n<ul>\n<li>Good quality data &#8211; Binding<\/li>\n<li>Good quality data &#8211; No binding<\/li>\n<li>Poor quality data &#8211; Check data<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1484828983369{margin-bottom: 25px !important;}&#8221;][vc_column_text]The MicroCal PEAQ-ITC Automated is a configurable, low volume, highly sensitive isothermal titration calorimeter which offers<\/p>\n","protected":false},"featured_media":3595,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"product_brand":[],"product_cat":[156,243],"product_tag":[1456,1533,1534,1535,1536,1537,1458,1538,1539,1540,1541,1542,1211,1418,1543,1544,1545,1468,1546,1547,1549,1548,1550,1466,1552,1551,1554,1553,1555,1556,1470,1557,1474,1559,1558,1560,1561,1562,1563,1564,1565,1566,1567,1569,1570,1571,1572,1573,1574,1575,1577,1576,1578,1580,1579,1581,1582,1583,1584,1585,1586,1587,1588,1589,1490,1590,1591,1592,1593,1594,1595,1596,1597,1598,1599,1568,1600,1601,1602,1603,1604,1605,1606,1607,1608,1609,1610,1611,1612,1239,1614,1613,1511,1615,1617,1616,1618,1619,1621,1620,1622,1623,1626,1624,1625,1627,1628,1629,1630,1631,1632,1633,1634,1635,1636,1637],"class_list":{"0":"post-1884","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-mikrokalorimeter-von-malvern-panalytical","7":"product_cat-mikrokalorimeter-von-malvern-panalytical-life-sciences","8":"product_tag-affinitaet","9":"product_tag-affinitaet-millimolar","10":"product_tag-affinitaet-nanomolar","11":"product_tag-affinitaet-pikomolar","12":"product_tag-affinitaetsbereich","13":"product_tag-affinitaetswerte","14":"product_tag-affinity","15":"product_tag-affinity-millimolar","16":"product_tag-affinity-nanomolar","17":"product_tag-affinity-picomolar","18":"product_tag-affinity-range","19":"product_tag-affinity-values","20":"product_tag-antibodies","21":"product_tag-antibody","22":"product_tag-antibody-binding","23":"product_tag-antikoerper-antikoerperbindung","24":"product_tag-aufeinanderfolgende-bindungsstellen","25":"product_tag-binding-affinity","26":"product_tag-binding-enthalpy","27":"product_tag-binding-entropy","28":"product_tag-binding-event","29":"product_tag-binding-events","30":"product_tag-binding-parameters","31":"product_tag-bindungsaffinitaet","32":"product_tag-bindungsenthalpie","33":"product_tag-bindungsenthalpie-messen","34":"product_tag-bindungsentropie","35":"product_tag-bindungsentropie-messen","36":"product_tag-bindungsereignisse","37":"product_tag-bindungsparameter","38":"product_tag-bio-molecular-interactions","39":"product_tag-biochemical-interaction","40":"product_tag-biochemische-wechselwirkung","41":"product_tag-biomolecular-binding","42":"product_tag-biomolecular-binding-events","43":"product_tag-biomolecular-interaction","44":"product_tag-biomolecular-interactions","45":"product_tag-biomolecules","46":"product_tag-biomolekulare-interaktionen","47":"product_tag-biomolekulare-wechselwirkung","48":"product_tag-biomolekuele","49":"product_tag-characterization-of-molecular-interactions","50":"product_tag-charakterisierung-molekularer-wechselwirkungen","51":"product_tag-chemische-reaktion-thermodynamik-messen","52":"product_tag-competing-bindings","53":"product_tag-competitive-binding","54":"product_tag-consecutive-binding-sites","55":"product_tag-dissociation","56":"product_tag-dissoziation","57":"product_tag-eine-bindungsstelle","58":"product_tag-enthalpie","59":"product_tag-enthalpie-messen","60":"product_tag-enthalpy","61":"product_tag-entropie","62":"product_tag-entropie-messen","63":"product_tag-entropy","64":"product_tag-enzyme-kinetics","65":"product_tag-enzymkinetik","66":"product_tag-hastelloy","67":"product_tag-interaction","68":"product_tag-isothermal-titration-calorimeter","69":"product_tag-isothermal-titration-calorimetry","70":"product_tag-isotherme-titrationskalorimetrie","71":"product_tag-isothermes-titrationskalorimeter","72":"product_tag-kd","73":"product_tag-konkurrierende-bindungen","74":"product_tag-label-free-measurement","75":"product_tag-lipide","76":"product_tag-lipids","77":"product_tag-low-molecular-weight-compounds","78":"product_tag-markierungsfreie-messung","79":"product_tag-measure-binding-enthalpy","80":"product_tag-measure-binding-entropy","81":"product_tag-measure-enthalpy","82":"product_tag-measure-entropy","83":"product_tag-measure-thermodynamics-chemical-reaction","84":"product_tag-mehrere-bindungsstellen","85":"product_tag-microcal-peaq-itc-microcal","86":"product_tag-molecular-interaction","87":"product_tag-molekulare-wechselwirkung","88":"product_tag-multiple-binding-sites","89":"product_tag-niedermolekulare-verbindungen","90":"product_tag-nucleic-acid","91":"product_tag-nukleinsaeure","92":"product_tag-one-binding-site","93":"product_tag-one-set-of-sites","94":"product_tag-peaq-itc","95":"product_tag-protein-protein-interaction-protein-protein-interaktion","96":"product_tag-protein-protein-wechselwirkung-proteins","97":"product_tag-proteine","98":"product_tag-sequential-binding","99":"product_tag-sequential-binding-sites","100":"product_tag-small-molecules","101":"product_tag-small-ubiquitin-like-modifier","102":"product_tag-stoechiometrie","103":"product_tag-stoechiometrie-n","104":"product_tag-stoechiometrisches-verhaeltnis","105":"product_tag-stoichiometric-ratio","106":"product_tag-stoichiometry","107":"product_tag-stoichi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