NanoSight NS300

The Malvern NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.

The NS300 allows rapid, automated analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type.

With the ability to be supplied with interchangeable laser modules and the introduction of a motorized 6 place filter wheel means different fluorescent labels can be analyzed. Sample temperature is fully programmable through the Nanoparticle Tracking Analysis (NTA) software.

Infos / Datasheet

  • Simultaneous measurement of multiple characteristics, saving time and sample volume.
  • Visual validation of results gives extra confidence.
  • User friendly software with easy set up of SOPs for routine use.
  • Minimal sample preparation.
  • On board temperature control.
  • Choice of laser wavelengths.
  • Choice of up to 6 different filters in a motorized wheel provides flexible fluorescence detection capability.


The Malvern Panalytical NanoSight syringe pump is available for all Malvern Panalytical NanoSight systems, enabling users to perform sample analysis at a constant flow rate.

This single syringe pump module is recommended for the flow-controlled detection of the fluorescent signal from many fluorescently-labeled particles. The NTA software automatically compensates for flow in the sample whilst conducting an analysis.

  • Flow detection of fluorescent signal reduces effect of photo photobleaching.
  • Automated analysis of multiple low concentration samples.

Fields of Application

Exosomes and Extracellular Microvesicles Characterization
Intracellular Communication
Diagnostics and Therapeutic Potential
Biomarker in Cancer Studies

Nanomedicine – Drug Delivery, Targeting and Controlled Release
nanoparticle vectors like: liposomes, microvesicles, micelles, dendrimers, solid lipid NPs, metallic NPs, semiconductor NPs and polymeric NPs are widely used to deliver drugs, genes, RNA and DNA, vaccines and diagnostics into specific cells/tissues

Protein Aggregation
Monitoring of aggregates and other sub-micron particulates in pharmaceutical products like antibody preparations

Viruses, Phages, Virus-Like Particles and Viral Vaccines
Virus characterization, sizing and concentration measurement
Total virus titer in minutes
Degree of aggregation

Tribology of Orthopaedic Implant Wear Particles

Characterization of Nanobubbles and Other Ultrafine Bubbles

Testing of Filters and Filtration Processes

Exceed the Lower Size Limit of Flow Cytometry

Nanoparticle Design and Production of Engineered NanoParticles (ENPs) and Nanomaterials
Nanoparticle metals, metal oxides and alloys
Carbon and Carbon Nanotubes
Nanoparticle-based biosensor
Superparamagnetic NPs for drug delivery and as magnetic resonance imaging
contrast agents

Healthcare and Environmental Issues of Nanoparticles
Study of Nanoparticle Toxicity and Environmental Impact
Studies at the Cellular Level – Cytotoxic and Genotoxicity
Aquatic and Marine Toxicity
Effect on Microorganisms, Microbiota and Plants
Wastewater Analysis
Monitoring and Treatment of Wastes and Contamination
Carbon Black and Related Diesel Exhaust Nanoparticles in Human Epithelial Cells
Determination of Engineered Nanoparticles and Nanoscale Components
in Food, Cosmetics and Customer Products,
on Textiles and in Textile Waste-Water,
in Papers, Inks, Printings and Coatings